Northstar’s Renova™ Cortical Stimulation System* is designed to treat neurological disorders by delivering targeted stimulation to the cerebral cortex. The cerebral cortex is located on the outer surface of the brain and plays a central role in many complex brain functions including movement, behavior, perceptual awareness, language, vision and hearing.

Stimulation is delivered to the appropriate site depending on the disorder being treated. Stimulation is controlled by a clinician and cannot be felt by the patient. Currently, Northstar is investigating the safety and efficacy of cortical stimulation for patients with post-stroke speech and motor deficits, major depression disorder and tinnitus.

• The Renova-ST™ Cortical Stimulation System is designed to enhance recovery of stroke patients who suffer from hemiparesis (weakness or loss of movement on one side of the body) and Broca’s aphasia (difficulty speaking). During a stroke, portions of the brain are damaged. Neural pathways which may be adjacent to or near the damaged area will attempt to compensate for the loss of function, a concept called neuroplasticity. Cortical stimulation is delivered to this new neuroplastic area, to encourage and enhance motor function during rehabilitation.

• The Renova-TT™ Cortical Stimulation System is designed to treat tinnitus. Tinnitus is the perception of sound in the ears or head where no external source is present and can be extremely debilitating. The Renova-TT™ System delivers targeted stimulation to the auditory cortex, the portion of the brain’s surface responsible for perceiving sound.

• The Renova-DT™ Cortical Stimulation System is designed to treat major depressive disorder. The Renova-DT™ System delivers targeted stimulation to the prefrontal cortex, the portion of the brain’s surface associated with behavior and emotion.

*Caution: Investigational device. Limited by Federal (or U.S.) law to investigational use.